Oregon State athletic director Bob De Carolis will step down after 17 years at the school.
He announced the decision in an open letter Monday in which he made it clear he is not retiring.
"As a next step, I look forward to my upcoming adventures in the world of intercollegiate athletics," said De Carolis, who spent the past 12 years as AD.
De Carolis was diagnosed with Parkinson's disease in 2011, but a spokesman confirmed the resignation is not health related.
Oregon State president Edward Ray will enlist an advisory group to find a replacement, the school announced, and will name an interim director should a permanent replacement not be found before De Carolis' final day on June 30.
During De Carolis' tenure, Oregon State completed an expansion to Reser Stadium and renovated or built up 10 other athletic centers on campus. The athletic department budget has grown from $29 million in 2002 to $71.3 million. He was named the Pac-12 Athletic Director of the Year for the 2009-10 school year.
Before his time in Corvallis, De Carolis worked in various capacities in the athletic department at Michigan for nearly 20 years.
"I have been extremely fortunate to have spent the last 17 years at Oregon State University," De Carolis said. "My family and I thank you for the opportunity, your support and friendship. I also want to thank the community of Corvallis; you were right when you said Corvallis is a great place to raise your family. We have enjoyed our time supporting the Beavers and will cherish the memories. We wish you all the best and GO BEAVS!"
The Associated Press contributed to this report.